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Miles Laboratories was founded as the Dr. Miles Medical Company in Elkhart, Indiana, in 1884 by Dr. Franklin L. Miles, a specialist in the treatment of eye and ear disorders, with an interest in the connection of the nervous system to overall health. The company is known for inventing products such as Alka-Selzer and One-A-Day vitamins. [1]
Vitamin A status involves eye health via two separate functions. Retinal is an essential factor in rod cells and cone cells in the retina responding to light exposure by sending nerve signals to the brain. An early sign of vitamin A deficiency is night blindness. [6] Vitamin A in the form of retinoic acid is essential to normal epithelial cell ...
The Vitamin Shoppe held an initial public offering on October 26, 2009. [7] The company made $751.5 million in net sales in fiscal 2010 and had a market capitalization of over $1 billion. [ 8 ] Since attaining its peak in February 2013, the stock has lost more than 90% of its value as of August 2017.
Vitamin World, Inc. was founded in 1977 as a subsidiary of NBTY Inc, later the Nature's Bounty Company. [1] NBTY manufactured and sold vitamin and mineral supplement products under the "Vitamin World" label, sports nutrition products under their "Precision Engineered" label, and numerous National Brand label products at the stores.
The First Nations nutrition experiments were a series of experiments run in Canada by Department of Pensions and National Health (now Health Canada) in the 1940s and 1950s. The experiments were conducted on at least 1,300 Indigenous people across Canada, approximately 1,000 of whom were children. [1]
Preformed vitamin A is fat-soluble and high levels have been reported to affect metabolism of the other fat-soluble vitamins D, [24] E, and K. The toxic effects of preformed vitamin A might be related to altered vitamin D metabolism, concurrent ingestion of substantial amounts of vitamin D, or binding of vitamin A to receptor heterodimers ...
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The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
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