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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain . [ 2 ]

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  5. Neurologists reveal 15 subtle migraine symptoms — that aren't ...

    www.aol.com/news/neurologists-reveal-15-subtle...

    For example, the Mayo Clinic says, you might see: Blind spots, which might be outlined with geometric designs. Shimmering stars or spots. Zigzag lines that slowly float across your vision. Flashes ...

  6. Deep vein thrombosis - Wikipedia

    en.wikipedia.org/wiki/Deep_vein_thrombosis

    Rivaroxaban is taken once daily, and apixaban is taken twice daily. [5] Warfarin, dabigatran, and edoxaban require the use of a parenteral anticoagulant to initiate oral anticoagulant therapy. [ 19 ] [ 125 ] When warfarin is initiated for VTE treatment, a 5-day minimum of a parenteral anticoagulant [ j ] together with warfarin is given, which ...

  7. Why Bill Gates Is Telling All About Life Before His Billions ...

    www.aol.com/why-bill-gates-telling-life...

    Microsoft founder Bill Gates is telling his “origin story” in his own words with the memoir Source Code, being released on Feb. 4 "My parents and early friends put me in a position to have a ...

  8. 2-Year-Old Girl and Mom Murdered, and 2 Other Children ...

    www.aol.com/2-old-girl-mom-murdered-151150267.html

    A man was killed by police after they say he fatally shot his wife and their 2-year-old daughter, and also injured their two other children, in Louisiana.

  9. Andexanet alfa - Wikipedia

    en.wikipedia.org/wiki/Andexanet_alfa

    Andexanet alfa, sold under the brand name Andexxa among others, is an antidote for the medications rivaroxaban and apixaban, when reversal of anticoagulation is needed due to uncontrolled bleeding. [8] It has not been found to be useful for other factor Xa inhibitors. [9] It is given by injection into a vein. [9]

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