Search results
Results from the WOW.Com Content Network
H1299, also known as NCI-H1299 [1] [2] or CRL-5803, [3] is a human non-small cell lung carcinoma cell line derived from the lymph node, which is widely used in research. [ 4 ] As with other immortalized cell lines, H1299 cells can divide indefinitely.
Originally the cell line was named MCF-7/ADR-RES; it was renamed together with the change in classification. [8] Two brain cancer cell lines, SNB-19 and U251, were discovered to come from the same person. [9] This makes a mixup likely. A 61st cell line, MDA-N, has been confirmed to being derived from the misclassified MDA-MB-435 cell line. [7]
Scientists study the behaviour of isolated cells grown in the laboratory for insights into how cells function in the body in health and disease. Experiments using cell culture are used for developing new diagnostic tests and new treatments for diseases. This is a list of major breast cancer cell lines that are primarily used in breast cancer ...
This list, containing 488 cell lines, was last updated on 1 December 2016. [c] Cellosaurus also is maintaining a list of "problematic" cell lines. [6] The list is dynamically generated from all cell lines in the database with a comment containing the dedicated words "Problematic cell line". As of 17 January 2017, the list contains 757 entries.
This page was last edited on 23 November 2019, at 17:55 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Immortalised cell lines are widely used as a simple model for more complex biological systems – for example, for the analysis of the biochemistry and cell biology of mammalian (including human) cells. [2] The main advantage of using an immortal cell line for research is its immortality; the cells can be grown indefinitely in culture.
Human isogenic disease models have been likened to 'patients in a test-tube', since they incorporate the latest research into human genetic diseases and do so without the difficulties and limitations involved in using non-human models. [2] Historically, cells obtained from animals, typically mice, have been used to model cancer-related pathways.
Vero 76 (ATCC No. CRL-1587) Isolated from Vero in 1968, it grows to a lower saturation density (cells per unit area) than the original Vero. It is useful for detecting and counting hemorrhagic fever viruses by plaque assays. Vero E6, also known as Vero C1008 (ATCC No. CRL-1586) This line is a clone from Vero 76.