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Serious side effects may include anaphylaxis, liver problems, depression, and muscle breakdown. [4] [5] Use in pregnancy and breastfeeding is of unclear safety. [10] Ezetimibe works by decreasing cholesterol absorption in the intestines. [5] Ezetimibe was approved for medical use in the United States in 2002. [4] It is available as a generic ...
The combination of vitamin D and vitamin K supplements has been shown in trials to improve bone quality. [79] As high intake of vitamin D is a cause of raised calcium levels (hypercalcemia), the addition of vitamin K may be beneficial in helping to prevent vascular calcification, particularly in people with chronic kidney disease. [80] [81]
Vitamin D (the inactive version) is mainly from two forms: vitamin D 3 and vitamin D 2. Vitamin D 3, or cholecalciferol, is formed in the skin after exposure to sunlight or ultra violet radiation or from D 3 supplements or fortified food sources. Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3]
A new study found that taking vitamin D supplements was associated with lower blood pressure. People with obesity and high blood pressure got the best results . Better calcium regulation may be ...
While some studies have found that vitamin D 3 raises 25(OH)D blood levels faster and remains active in the body longer, [44] [45] others contend that vitamin D 2 sources are equally bioavailable and effective for raising and sustaining 25(OH)D. [46] [47] If digestive disorders compromise absorption, then intramuscular injection of up to ...
Calcium forms complexes with a number of pharmaceutical drugs, reducing their bioavailability; among them are tetracyclines, quinolone antibiotics, levothyroxine, and bisphosphonates, as well as iron, magnesium and zinc supplements. Vitamin D in usual doses has no relevant interactions. [2]
Jaundice, a common side effect caused by vitamin K antagonists. Drugs that inhibit the formation of the vitamin K-dependent clotting factors and hence thrombin, an endogenous protein involved in the coagulation cascade. Vitamin K is an essential cofactor for the synthesis of clotting factors.
Common side effects include constipation and nausea. [1] When taken by mouth high blood calcium is uncommon. [1] Calcium supplements, unlike calcium from dietary sources, appear to increase the risk of kidney stones. [1] Adults generally require about a gram of calcium a day. [1] Calcium is particularly important for bones, muscles, and nerves. [1]