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Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. [ 6 ] [ 7 ] Specifically it is used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. [ 6 ]
In October 2010 the US FDA approved dabigatran etexilate for the prevention of stroke in patients with atrial fibrillation (AF). [6] [10] Many pharmaceutical companies have attempted to develop orally bioavailable DTI drugs but dabigatran etexilate is the only one to reach the market. [9]
Dabigatran is an oral direct thrombin inhibitor. Dabigatran (Pradaxa) was found to be noninferior to Warfarin in prevention of ischemic stroke, as well as intracranial hemorrhage risk and overall mortality for non-valvular atrial fibrillation according to the RE-LY trial.
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After Stark County reported its sixth consecutive increase in overdose deaths in 2023, local health officials say 2024 appears promising. Drug overdose deaths down in Ohio, but increase in Stark ...
There was a 5% decrease in unintentional drug overdose deaths in Ohio in 2022, according to a new report. But they rose in Stark County. Overdose deaths drop in Ohio, but increase in Stark County.
Direct factor Xa inhibitors (xabans) are anticoagulants (blood thinning drugs), used to both treat and prevent blood clots in veins, and prevent stroke and embolism in people with atrial fibrillation (AF). [2] [3]
The Ohio Department of Health’s annual Unintentional Drug Overdose Report showed a 9% decline in verified overdose deaths across the state. In 2023, there were 4,452 unintentional drug overdose ...
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