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HATU was first reported by Louis A. Carpino in 1993 as an efficient means of preparing active esters derived from 1-hydroxy-7-azabenzotriazole (HOAt). [2] HATU is commonly prepared from HOAt and TCFH under basic conditions [3] and can exist as either the uronium salt (O-form) or the less reactive iminium salt (N-form).
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.
In vivo dermal sensitization studies according to OECD 429 [10] confirmed HBTU is a moderate skin sensitizer, showing a response at 0.9 wt% in the Local Lymph Node Assay (LLNA) placing it in Globally Harmonized System of Classification and Labelling of Chemicals (GHS) Dermal Sensitization Category 1A. [11]
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Ancient Greek had the term τέκνή γραμματική (téchnē grammatikḗ, 'skill in the use of letters'), which was adapted into Latin as ars grammatica.This term was used in the title of works about writing and language, which came to be known in English as grammar-books or grammars.
The first published English grammar was a Pamphlet for Grammar of 1586, written by William Bullokar with the stated goal of demonstrating that English was just as rule-based as Latin. Bullokar's grammar was faithfully modeled on William Lily's Latin grammar, Rudimenta Grammatices (1534), used in English schools at that time, having been ...
About Wikipedia; Contact us; Contribute Help; ... English grammar: Dewey Decimal: 425: ... English grammar books (14 P)
Water (H 2 O) is a polar inorganic compound that is at room temperature a tasteless and odorless liquid, which is nearly colorless apart from an inherent hint of blue.It is by far the most studied chemical compound [20] and is described as the "universal solvent" [21] and the "solvent of life". [22]