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Abnormal dreams; Aggression; Anaphylactic shock; Angioedema (indicative of a hypersensitivity reaction); Arthralgia; Ataxia; Blood glucose disturbances; Bronchospasm (indicative of a hypersensitivity reaction)
Bupropion, formerly called amfebutamone, [16] and sold under the brand name Wellbutrin among others, is an atypical antidepressant that is indicated in the treatment of major depressive disorder, seasonal affective disorder and to support smoking cessation.
Wellbutrin and other antidepressants may cause an increase in risk of suicide in young adults. If you start to feel suicidal after using Wellbutrin, it’s important to seek professional medical ...
The cause of serotonin toxicity or accumulation is an important factor in determining the course of treatment. Serotonin is catabolized by monoamine oxidase A in the presence of oxygen , so if care is taken to prevent an unsafe spike in body temperature or metabolic acidosis, oxygenation will assist in dispatching the excess serotonin.
Wellbutrin is the brand name for bupropion, a prescription-only antidepressant. Wellbutrin is typically sold in a tablet form that works by increasing the activity of natural chemicals called ...
The dose of bupropion in the study was lower than the target dose recommended for clinical practice. [10] In this study, dextromethorphan/bupropion showed significantly greater improvement than bupropion alone in the first two weeks of treatment but not by week 6 of treatment in people with major depressive disorder.
Bupropion has been known to cause seizures in high therapeutic doses and in acute overdoses. For example a 16 year old ingested 1.5 g and developed seizures and cardiotoxicity. [77] There are retrospective case series with good information on dose effect relationships [78] [79] which could be used in the article.
Both newer and older drugs are generally equally effective in new onset epilepsy. [42] The newer drugs tend to have fewer side effects. [ 42 ] For newly diagnosed partial or mixed seizures , there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy . [ 42 ]