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Injection site reactions (ISRs) are reactions that occur at the site of injection of a drug. They may be mild or severe and may or may not require medical intervention. Some reactions may appear immediately after injection, and some may be delayed. [1] Such reactions can occur with subcutaneous, intramuscular, or intravenous administration.
Medication administered via intramuscular injection is not subject to the first-pass metabolism effect which affects oral medications. Common sites for intramuscular injections include the deltoid muscle of the upper arm and the gluteal muscle of the buttock. In infants, the vastus lateralis muscle of the thigh is commonly used. The injection ...
A diagnosis of functional PAES is made if symptoms are improved after Botulinum injection. However, If symptoms are persisted, the patient can undergo an additional Botulinum injection or proceed with surgical decompression. [27] The outcome following the surgery is usually favorable. Successful resolution of PAES occurs in 77 percent of cases ...
Patients also frequently report persistent or intermittent pain or dysthesias in posterior hip, buttocks, or thigh. [4] Unlike discogenic sciatica (caused by the spine), patients with deep gluteal syndrome report exacerbation of symptoms with pressure in the buttocks, such as tenderness or pain on deep palpation, or pain on prolonged sitting.
The diagnosis is confirmed when the patient reports a significant change in relief from pain and the diagnostic injection is performed on two separate visits. Published studies have used at least a 75 percent change in relief of pain before a response is considered positive and the sacroiliac joint deemed the source of pain.
Symptoms are typically unilateral, seen in about 78% of cases, but may be bilateral. [4] [2] The most common symptom is pain, paresthesias, or dysthesias on the anterolateral surface of the thigh that extends just above the knee. [3] [8] [5] [2] [6] [4] (The term "meralgia paraesthetica" combines four Greek roots to mean "thigh pain with ...
There are five signs and symptoms of acute compartment syndrome. [7] They are known as the "5 Ps": pain, pallor, decreased pulse, paresthesia, and paralysis. [7] Pain and paresthesia are the early symptoms of compartment syndrome. [19] [7] Common symptoms are: Pain: A person may feel pain greater than the exam findings. [7]
Injection fibrosis is a complication of intramuscular injection, occurring especially often in infants and children. Injections are often delivered to the quadriceps, triceps, and gluteal muscles, and thus the complication often manifests itself in those muscles. Patients are unable to fully flex the affected muscle. The condition is painless ...