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Combined use of medications with anticholinergics may cause synergistic (supra-additive), additive, or antagonistic interactions, leading to no therapeutic effect or overdosing. [25] [26] Below listed are some medications or food that can interact with anticholinergics. Medications indicated for: Irregular heartbeat, e.g. disopyramide ...
Drugs with muscarinic antagonist activity are widely used in medicine, in the treatment of low heart rate, overactive bladder, respiratory problems such as asthma and chronic obstructive pulmonary disease (COPD), and neurological problems such as Parkinson's disease and Alzheimer's disease. A number of other drugs, such as antipsychotics and ...
Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
ChEIs may be used as drugs for Alzheimer's and myasthenia gravis, and also as chemical weapons and insecticides. [ 4 ] [ 5 ] Side effects when used as drugs may include loss of appetite , nausea , vomiting , loose stools , vivid dreams at night, dehydration , rash , bradycardia , peptic ulcer disease , seizures , weight loss , rhinorrhea ...
As an antidote to anticholinergic poisoning; To reverse the effect of non-depolarising muscle relaxants; To treat neuropsychiatric symptoms of diseases such as Alzheimer's disease, particularly apathy; To increase chances of lucid dreaming (by prolonging REM sleep) [10] To treat Alzheimer's disease, the Lewy body dementias and Parkinson's disease.
Biological Toxins such as Diphtheria toxin [18]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [19] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
These drugs work to increase the levels of acetylcholine and subsequently increase the function of neural cells. [8] However, not all treatments based upon the cholinergic hypothesis have been successful in treating the symptoms or slowing the progression of AD. [9]
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