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The heart wall is a three-layered structure with a thick layer of myocardium sandwiched between the inner endocardium and the outer epicardium (also known as the visceral pericardium). The inner endocardium lines the cardiac chambers, covers the cardiac valves , and joins with the endothelium that lines the blood vessels that connect to the heart.
The visceral serous pericardium, also known as the epicardium, covers the myocardium of the heart [8] and can be considered its serosa. It is largely made of a mesothelium overlying some elastin-rich loose connective tissue. During ventricular contraction, the wave of depolarization moves from the endocardial to the epicardial surface.
The endocardium, by secreting endothelins, may also play a role in regulating the contraction of the myocardium. [8] The swirling pattern of myocardium helps the heart pump effectively. The middle layer of the heart wall is the myocardium, which is the cardiac muscle—a layer of involuntary striated muscle tissue surrounded by a framework of ...
Trabeculae lie at the interface between intracardiac flow and the compact myocardium. Their fractal branching pattern helps to maintain cardiac performance in both healthy and failing hearts by increasing contractility and stroke work. [ 3 ]
The right fibrous trigone is continuous with the central fibrous body. This is the strongest part of the fibrous cardiac skeleton. The upper chambers and lower are electrically divided by the properties of collagen proteins within the rings. The valve rings, central body, and skeleton of the heart consisting of collagen are impermeable to ...
Cardiac physiology or heart function is the study of healthy, unimpaired function of the heart: involving blood flow; myocardium structure; the electrical conduction system of the heart; the cardiac cycle and cardiac output and how these interact and depend on one another.
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
Intercalated discs are complex structures that connect adjacent cardiac muscle cells.The three types of cell junction recognised as making up an intercalated disc are desmosomes, fascia adherens junctions, and gap junctions.