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ChIP-seq technology is currently seen primarily as an alternative to ChIP-chip which requires a hybridization array. This introduces some bias, as an array is restricted to a fixed number of probes. Sequencing, by contrast, is thought to have less bias, although the sequencing bias of different sequencing technologies is not yet fully ...
One notable example of functional selectivity occurs with the 5-HT 2A receptor, as well as the 5-HT 2C receptor. Serotonin, the main endogenous ligand of 5-HT receptors, is a functionally selective agonist at this receptor, activating phospholipase C (which leads to inositol triphosphate accumulation), but does not activate phospholipase A2, which would result in arachidonic acid signaling.
Bias The bias direction of a piece of woven fabric, usually referred to simply as "the bias", is at 45 degrees to its warp and weft threads. Every piece of woven fabric has two biases, perpendicular to each other. Non-woven fabrics such as felt or interfacing do not have a bias. bias tape Bias tape or bias binding is a narrow strip of fabric ...
CUT&RUN is an alternative to the current standard of ChIP-seq. ChIP-Seq suffers from limitations due to the cross linking step in ChIP-Seq protocols that can promote epitope masking and generate false-positive binding sites. [1] [2] As well, ChIP-seq suffers from suboptimal signal-to-noise ratios and poor resolution. [3]
ChIL-Seq is an alternative to the current standard of ChIP-seq. ChIP-Seq suffers from limitations due to the cross linking step in ChIP-Seq protocols that can promote epitope masking and generate false-positive binding sites. [2] [3] As well, ChIP-seq suffers from suboptimal signal-to-noise ratios and poor resolution. [4]
The scents of cinnamon and star anise add big flavors to this quick soup. Butter adds body and a silky texture. Fresh udon noodles take only a few minutes to cook, but dry udon noodles work well ...
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Extra-wide double-fold bias tape being sewn as a binding on a decorative quilt An example of single-fold bias tape An example of double-fold bias tape Commercial bias binding foot fed with bias binding, producing bias binding tape. Bias tape or bias binding is a narrow strip of fabric, typically plain weave, cut on the bias.