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THC, the main psychoactive component of cannabis, may only be detectable in saliva and oral fluid for 2–24 hours in most cases. [8] [9] The main metabolite excreted in the urine is 11-Nor-9-carboxy-THC, also known as THC-COOH. Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. [10]
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As of 2021, cannabis is the most commonly consumed federally illegal drug in the United States, with 36.4 million people (aged 10 years or older) consuming it monthly. [2] In addition to being smoked and vaporized, cannabis and its active cannabinoids may be ingested, placed under the tongue, or applied to the skin.
Most are lipid-soluble, non-polar, small molecules (usually 20–26 carbon atoms) that are fairly volatile, making them "smokable", like THC. [50] Another common feature of most synthetic cannabinoids and THC is a side-chain of five to nine saturated carbon atoms.
Cannabis is the most widely used illicit drug in the Western world. [3] In the United States, 10-20% of those who begin the use of cannabis daily will later become dependent. [4] [5] Cannabis use can lead to addiction, which is defined as "when the person cannot stop using the drug even though it interferes with many aspects of his or her life."
Cannabis Station, a medical cannabis dispensary in Denver, Colorado Cannabis flower stored in jars at a dispensary in Colorado. Cannabis dispensaries in the United States or marijuana dispensaries are a type of cannabis retail outlet, local government-regulated physical location, typically inside a retail storefront or office building, in which a person can purchase cannabis and cannabis ...
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The method of obtaining medical cannabis varies by region and by legislation. In the US, most consumers grow their own or buy it from cannabis dispensaries in states where it is legal. [6] [138] Marijuana vending machines for selling or dispensing cannabis are in use in the United States and are planned to be used in Canada. [139]