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  2. Nondisjunction - Wikipedia

    en.wikipedia.org/wiki/Nondisjunction

    In general, nondisjunction can occur in any form of cell division that involves ordered distribution of chromosomal material. Higher animals have three distinct forms of such cell divisions: Meiosis I and meiosis II are specialized forms of cell division occurring during generation of gametes (eggs and sperm) for sexual reproduction, mitosis is the form of cell division used by all other cells ...

  3. Klinefelter syndrome - Wikipedia

    en.wikipedia.org/wiki/Klinefelter_syndrome

    The extra chromosome is retained because of a nondisjunction event during paternal meiosis I, maternal meiosis I, or maternal meiosis II, also known as gametogenesis. The relevant nondisjunction in meiosis I occurs when homologous chromosomes, in this case the X and Y or two X sex chromosomes, fail to separate, producing a sperm with an X and a ...

  4. Meiosis - Wikipedia

    en.wikipedia.org/wiki/Meiosis

    When the segregation is not normal, it is called nondisjunction. This results in the production of gametes which have either too many or too few of a particular chromosome, and is a common mechanism for trisomy or monosomy. Nondisjunction can occur in the meiosis I or meiosis II, phases of cellular reproduction, or during mitosis.

  5. Homologous chromosome - Wikipedia

    en.wikipedia.org/wiki/Homologous_chromosome

    1. Meiosis I 2. Meiosis II 3. Fertilization 4. Zygote Nondisjunction is when chromosomes fail to separate normally resulting in a gain or loss of chromosomes. In the left image the blue arrow indicates nondisjunction taking place during meiosis II. In the right image the green arrow is indicating nondisjunction taking place during meiosis I.

  6. Karyotype - Wikipedia

    en.wikipedia.org/wiki/Karyotype

    [1] [2] Karyotyping is the ... Numerical abnormalities, also known as aneuploidy, often occur as a result of nondisjunction during meiosis in the formation of a ...

  7. Oocyte abnormalities - Wikipedia

    en.wikipedia.org/wiki/Oocyte_abnormalities

    Oocyte abnormalities can be caused by a variety of genetic factors affecting different stages in meiosis. [1] Moreover, ageing is associated with oocyte abnormalities since higher maternal age is associated with oocytes with a reduced gene expression of spindle assembly checkpoints which are important in maintaining stability in the genome.

  8. File:Nondisjunction Diagrams.svg - Wikipedia

    en.wikipedia.org/wiki/File:Nondisjunction...

    English: 1. Meiosis I 2. Meiosis II 3. Fertilization 4. Zygote The left image at the blue arrow is nondisjunction taking place during meiosis II. The right image at the green arrow is nondisjunction taking place during meiosis I. Nondisjunction is when chromosomes fail to separate normally resulting in a gain or loss of chromosomes.

  9. Talk:Nondisjunction - Wikipedia

    en.wikipedia.org/wiki/Talk:Nondisjunction

    The current article defines nondisjunction as "the failure of chromosome pairs to separate properly during meiosis stage 1 or stage 2, specifically in the anaphase." We could choose to keep this definition or improve upon it from our sources/references.