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Avian influenza, also known as avian flu or bird flu, is a disease caused by the influenza A virus, which primarily affects birds but can sometimes affect mammals including humans. [1] Wild aquatic birds are the primary host of the influenza A virus, which is enzootic (continually present) in many bird populations.
Influenza A virus subtype H5N1 (A/H5N1) is a subtype of the influenza A virus, which causes the disease avian influenza (often referred to as "bird flu"). It is enzootic (maintained in the population) in many bird populations, and also panzootic (affecting animals of many species over a wide area). [1]
A bird-adapted strain of H5N1, called HPAI A(H5N1) for "highly pathogenic avian influenza virus of type A of subtype H5N1", is the causative agent of H5N1 flu. HPAI A(H5N1) is considered an avian disease, although there is some evidence of limited human-to-human transmission of the virus. [2]
Bird flu can also cause respiratory and classic flu-like symptoms, including cough, runny nose, fever, sore throat, body aches, headaches, fatigue, shortness of breath, and pneumonia, the CDC says ...
What we think of as the seasonal flu in humans is caused by types A and B. Bird flu falls under the umbrella of influenza A viruses. The strain currently spreading in the U.S. is H5N1, an HPAI ...
Bird flu is a scary illness with a high mortality rate. But so far, infections in the U.S. have been relatively mild—until now. A patient in Louisiana has been hospitalized with a severe case of ...
In November 2013, the U.S. Food and Drug Administration (FDA) approved an experimental H5N1 bird flu vaccine to be held in stockpiles. [22] [23] In a clinical trial including 3,400 adults, 91% of people age 18–64 and 74% of people age 65 or older formed an immune response sufficient to provide protection. Reported adverse effects were ...
At baseline, bird flu is usually severe in humans. Of the 863 reported H5N1 bird flu cases reported worldwide between 2003 and 2021, 456 ended in death, according to data from the World Health ...