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Anterior ischemic optic neuropathy is commonly known as a "stroke of the optic nerve" and affects the optic nerve head (where the nerve exits the eyeball). There is usually a sudden loss of blood supply and nutrients to the optic nerve head. Vision loss is typically sudden and most commonly occurs upon waking up in the morning.
The central retinal artery supplies blood to all the nerve fibers that form the optic nerve, which carries the visual information to the lateral geniculate nucleus of the thalamus, including those that reach over the fovea. Its blood flow can be revealed by fluorescein angiography or laser Doppler imaging. [4]
The optic disc represents the beginning of the optic nerve and is the point where the axons of retinal ganglion cells come together. The optic disc in a normal human eye carries 1–1.2 million afferent nerve fibers from the eye toward the brain. The optic disc is also the entry point for the major arteries that supply the retina with blood ...
The anterior optic nerve receives blood primarily from the posterior ciliary arteries. The anterior optic nerve, a.k.a. the optic nerve head, is surrounded by the scleral canal, and is vulnerable to crowding of nerve fibers. The portion of the optic nerve head that is visible by looking into the eye with an ophthalmoscope is called the optic disc.
The exact mechanism of optic nerve ischemia in these cases remains unclear, but contributing factors may include hypotension, anemia, hypoxia, and changes in the autoregulation of optic nerve arterial blood flow. The incidence of ischemic optic neuropathy leading to vision loss following general surgeries ranges between 0.1% and 0.002%.
The optic nerve can be damaged when exposed to direct or indirect injury. Direct optic nerve injuries are caused by trauma to the head or orbit that crosses normal tissue planes and disrupts the anatomy and function of the optic nerve; e.g., a bullet or forceps that physically injures the optic nerve.
Design by MNT; Photography by Community Eye Health, CC BY-NC 2.0 & NurPhoto/Getty Images ... This condition, caused by a sudden loss of blood flow to the optic nerve, can result in severe and ...
As the fluid surrounding the optic nerve within its meningeal envelope is contiguous with the cerebrospinal fluid of the central nervous system, increased intracranial pressure can cause compression of the central retinal vein where it emerges from the optic nerve (the accompanying artery is meanwhile less susceptible to compression due to its thicker arterial wall), with the resulting venous ...