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Thereafter, the otic cup closes off, creating the otic vesicle. Once formed, the otic vesicle will reside next to the neural tube medially, and on the lateral side will be paraxial mesoderm. Neural crest cells will migrate rostral and caudal to the placode. The general sequence in formation of the otic vesicle is relatively conserved across ...
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The first part of the ear to develop is the inner ear, [19] which begins to form from the ectoderm around the embryo's 22nd day, [18] derived from two thickenings called otic placodes on either side of the head. Each otic placode recedes below the ectoderm, forms an otic pit and then an otic vesicle. [20]
Only the epidermis in the head is competent to respond to the signal from the optic vesicles. Both the optic vesicle and the head epidermis are required for eye development. The competence of the head epidermis to respond to the optic vesicle signals comes from the expression of Pax6 in the epidermis. Pax6 is necessary and sufficient for eye ...
The cochlear duct develops from the ventral otic vesicle (otocyst). [3] It grows slightly flattened between the middle and outside of the body. [3] This development may be regulated by the genes EYA1, SIX1, GATA3, and TBX1. [3] The organ of Corti develops inside the cochlear duct. [4]
The bony labyrinth (also osseous labyrinth or otic capsule) is the rigid, bony outer wall of the inner ear in the temporal bone. It consists of three parts: the vestibule, semicircular canals, and cochlea. These are cavities hollowed out of the substance of the bone, and lined by periosteum.