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Zaleplon, sold under the brand name Sonata among others, is a sedative and hypnotic which is used to treat insomnia. It is a nonbenzodiazepine or Z-drug of the pyrazolopyrimidine class. [ 10 ] It was developed by King Pharmaceuticals and approved for medical use in the United States in 1999.
Chronic insomnia often requires more comprehensive treatment to help you address underlying causes, implement healthy sleep habits and learn techniques to manage sleep-disrupting thoughts and ...
[61] [62] A meta-analysis of randomised controlled clinical trials that compared benzodiazepines to zopiclone or other Z drugs such as zolpidem and zaleplon has found few clear and consistent differences between zopiclone and the benzodiazepines in sleep onset latency, total sleep duration, number of awakenings, quality of sleep, adverse events ...
Although it is hypothesized that somnifacients may help treat depression caused by insomnia, data released by the Food and Drug Administration (FDA) shows that the use of nonbenzodiazepines including zolpidem, zaleplon and eszopiclone increased the risk of depression by over two times when compared to individuals taking placebo pills. [23]
Chemical structure of the prototypical Z-drug zolpidem. Nonbenzodiazepines (/ ˌ n ɒ n ˌ b ɛ n z oʊ d aɪ ˈ æ z ɪ p iː n,-ˈ eɪ-/ [1] [2]), sometimes referred to colloquially as Z-drugs (as many of their names begin with the letter "z"), are a class of psychoactive, depressant, sedative, hypnotic, anxiolytic drugs that are benzodiazepine-like in uses, such as for treating insomnia [3 ...
Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [ 3 ] [ 4 ] Evidence supports slight to moderate benefit up to six months. [ 5 ] [ 4 ] [ 6 ] It is taken by mouth .
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