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Aging skin is characterized by wrinkles, loss of skin flexibility, laxity, and having a rough appearance in the skin texture. Prevalent throughout the body, loss of collagen can also contribute to numerous other disorders such as joint pain, weakened hair and nails, reduced bone density, gastrointestinal issues, and reduced muscle mass ...
Elastic tissue loss, vascular and connective tissue degradation, and skin and cartilage thinning are all brought on by aging. [6] The onset of CNCH symptoms may be related to the cartilage's increased susceptibility to pressure damage as it ages and loses some of its flexibility. Additionally, older adults typically move less while they sleep ...
Sarcopenic obesity is a combination of two disease states, sarcopenia and obesity.Sarcopenia is the muscle mass/strength/physical function loss associated with increased age, [1] and obesity is based off a weight to height ratio or body mass index (BMI) that is characterized by high body fat or being overweight.
A number of expert groups have proposed an increase in dietary protein recommendations for older age groups to 1.0–1.2 g/kg body weight per day. [48] [49] Ensuring adequate nutrition in older adults is of interest in the prevention of sarcopenia and frailty, since it is a simple, low-cost treatment approach without major side effects. [50]
Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue. [1] The body's structures are held together by connective tissues, consisting of two distinct proteins : elastin and collagen .
Pseudoxanthoma elasticum (PXE) is a genetic disease that causes mineralization of elastic fibers in some tissues. The most common problems arise in the skin and eyes, and later in blood vessels in the form of premature atherosclerosis.
The primary sites of end-target organ damage following an increase in arterial stiffness are the heart, the brain (stroke, white matter hyperintensities (WMHs)), the placenta, and the kidneys (age-related loss of kidney function). [21] Firstly, stiffened arteries compromise the Windkessel effect of the arteries. [22]
Contractures develop usually when normally elastic tissues such as muscles or tendons are replaced by inelastic tissues . This results in the shortening and hardening of these tissues, ultimately causing rigidity, joint deformities and a total loss of movement around the joint.
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