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Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue (the graft). When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty .
Patients with failed corneal transplant using donor cornea and have little or no vision left. Patients with non-autoimmune diseases, congenital birth defects and other ocular problems. Patients who do not have access to corneal transplant tissue; Indications for non-penetrating keratoprostheses include the following: Keratoconus; Corneal ...
The four main types of tissue transplantation are xenotransplantation, allotransplantation, isotransplantation and autotransplantation, while the common tissues transplanted include skin, bone, corneal and vessel grafts. [3] Tissue transplantation comes with risks and complications, including immune rejection and viral infections.
Descemet membrane endothelial keratoplasty (DMEK) is a method of corneal transplantation that involves the removal of a thin sheet of tissue from the posterior (innermost) side of a person's cornea to replace it with the two posterior (innermost) layers of corneal tissue from a donor's eyeball.
PDEK is different from the whole cornea transplantation in which the transplantation of entire donor cornea to the recipient is done. [2] [3] Normal corneal thickness is about 520 to 540 microns in the centre and 600 to 620 microns in the periphery. [4] Pre descemet's layer which is dissected in PDEK, measures about 10.15±3.6 microns thick. [5]
The outer layer of the cornea, or epithelium, is a soft, rapidly regrowing layer in contact with the tear film that can completely replace itself from limbal stem cells within a few days with no loss of clarity. The deeper layers of the cornea, as opposed to the outer epithelium, are laid down early in life and have very limited regenerative ...
A Gundersen flap, also known as Gundersen's flap, Gundersen's conjunctival flap, or conjunctivoplasty, and often misspelled Gunderson, is a surgical procedure for correcting corneal disease. It involves excising a damaged section of cornea, and replacing it with a section (or "flap") of the patient's own conjunctiva. [1]
Corneal cross-linking (CXL) with riboflavin (vitamin B 2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, [2] PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. [3]