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2. Modified-release dosage - Wikipedia

   en.wikipedia.org/wiki/Modified-release_dosage

   Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). [1]

3. Metformin - Wikipedia

   en.wikipedia.org/wiki/Metformin

   Lactate uptake by the liver is diminished with metformin use because lactate is a substrate for hepatic gluconeogenesis, a process that metformin inhibits. In healthy individuals, this slight excess is cleared by other mechanisms (including uptake by unimpaired kidneys), and no significant elevation in blood levels of lactate occurs. [ 45 ]

4. Calcitriol - Wikipedia

   en.wikipedia.org/wiki/Calcitriol

   Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]

5. Diabetes medication - Wikipedia

   en.wikipedia.org/wiki/Diabetes_medication

   Metformin is a first-line medication used for treatment of type 2 diabetes. It is generally prescribed at initial diagnosis in conjunction with exercise and weight loss, as opposed to the past, where it was prescribed after diet and exercise had failed.

6. Are Diabetes Drugs Really Safe (& Reliable) for Weight Loss?

   www.aol.com/diabetes-drugs-really-safe-reliable...

   5. Metformin. Metformin — a biguanide — is an oral diabetes medication that helps keep blood sugar in check by causing the liver to produce less glucose. It was approved by the FDA in 1994 for ...

7. When Is the Best Time to Take Metformin? - AOL

   www.aol.com/best-time-metformin-141700387.html

   The best time depends on your metformin type and dosage. Extended-release metformin tablets are usually taken once a day with your evening meal. Some people take metformin once, twice, or even ...