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The salience network is theorized to mediate switching between the default mode network and central executive network. [1] [2]The salience network (SN), also known anatomically as the midcingulo-insular network (M-CIN) or ventral attention network, is a large scale network of the human brain that is primarily composed of the anterior insula (AI) and dorsal anterior cingulate cortex (dACC).
Salience (also called saliency, from Latin saliō meaning “leap, spring” [1]) is the property by which some thing stands out.Salient events are an attentional mechanism by which organisms learn and survive; those organisms can focus their limited perceptual and cognitive resources on the pertinent (that is, salient) subset of the sensory data available to them.
The salience network is theorised to mediate switching between the default mode network and frontoparietal network (central executive network). [1] [2] [3]The frontoparietal network (FPN), generally also known as the central executive network (CEN) or, more specifically, the lateral frontoparietal network (L-FPN) (see Nomenclature), is a large-scale brain network primarily composed of the ...
The salience network also integrates the ventral attention network in its function to respond to unexpected salient behavioral stimuli. [26] Salience Network dysfunction has been associated with schizophrenia, anxiety disorders, and Autism Spectrum Disorders. [27]
In neuroscience, the default mode network (DMN), also known as the default network, default state network, or anatomically the medial frontoparietal network (M-FPN), is a large-scale brain network primarily composed of the dorsal medial prefrontal cortex, posterior cingulate cortex, precuneus and angular gyrus.
The salience network is a cingulate-frontal operculum network that includes core nodes in the anterior cingulate and anterior insula. [162] A salience network is a large-scale brain network involved in detecting and orienting the most pertinent of the external stimuli and internal events being presented. [161]
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The salience network consists of several structures, including the anterior (bilateral) insula, dorsal anterior cingulate cortex, and three subcortical structures which are the ventral striatum, substantia nigra/ventral tegmental region. [26] [27] It plays the key role of monitoring the salience of external inputs and internal brain events.