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Methylxanthines are chemical compounds which are derivatives of xanthine with one or more methyl groups, including: One methyl group: 1-Methylxanthine;
Xanthine (/ ˈ z æ n θ iː n / or / ˈ z æ n θ aɪ n /, from Ancient Greek ξανθός xanthós ' yellow ' for its yellowish-white appearance; archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms. [2]
7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [ 1 ] [ 2 ] It is a non-selective antagonist of the adenosine receptors .
This is a list of species and genera that are used as entheogens or are used in an entheogenic concoction (such as ayahuasca). For ritualistic use they may be classified as hallucinogens. The active principles and historical significance of each are also listed to illustrate the requirements necessary to be categorized as an entheogen.
Plants with more than one significant human use may be listed in multiple categories. Plants are considered domesticated when their life cycle , behavior , or appearance has been significantly altered as a result of being under artificial selection by humans for multiple generations (see the main article on domestication for more information).
The plant contains chemicals that are toxic to animals including humans, but it has also been used as a medicine. All parts of the plant contain protoanemonin , which can cause severe skin and gastrointestinal irritation, bitter taste and burning in the mouth and throat, mouth ulcers, nausea, vomiting, diarrhea, and hematemesis .
Nathanson concluded that caffeine and related methylxanthines could be natural pesticides developed by plants as protection against worms: Caffeine is found in many plant species, with high levels in seedlings that are still developing foliage, but are lacking mechanical protection; [17] caffeine paralyzes and kills certain insects feeding upon ...
Alkaloid-containing plants have been used by humans since ancient times for therapeutic and recreational purposes. For example, medicinal plants have been known in Mesopotamia from about 2000 BC. [30] The Odyssey of Homer referred to a gift given to Helen by the Egyptian queen, a drug bringing oblivion.