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Nociception. In physiology, nociception (/ˌnəʊsɪˈsɛpʃ (ə)n/), also nocioception; from Latin nocere 'to harm /hurt') is the sensory nervous system 's process of encoding noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize ...
A nociceptor (from Latin nocere 'to harm or hurt'; lit. 'pain receptor') is a sensory neuron that responds to damaging or potentially damaging stimuli by sending "possible threat" signals [1][2][3] to the spinal cord and the brain. The brain creates the sensation of pain to direct attention to the body part, so the threat can be mitigated; this ...
Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C-nerve fibers, as well as free nerve endings) throughout the nervous system of an organism. The ability to perceive noxious stimuli is a prerequisite for nociception , which itself is a prerequisite for nociceptive pain . [ 1 ]
The somatosensory system, or somatic sensory system is a subset of the sensory nervous system. It has two subdivisions, one for the detection of mechanosensory information related to touch, and the other for the nociception detection of pain and temperature. [1] The main functions of the somatosensory system are the perception of external ...
Group C nerve fibers are one of three classes of nerve fiber in the central nervous system (CNS) and peripheral nervous system (PNS). The C group fibers are unmyelinated and have a small diameter and low conduction velocity, whereas Groups A and B are myelinated. Group C fibers include postganglionic fibers in the autonomic nervous system (ANS ...
Pain and pleasure. Some philosophers, such as Jeremy Bentham, Baruch Spinoza, and Descartes, have hypothesized that the feelings of pain (or suffering) and pleasure are part of a continuum. There is strong evidence of biological connections between the neurochemical pathways used for the perception of both pain and pleasure, as well as other ...
Nociplastic pain is a longterm complex pain, one of three mechanisms of pain, defined by the International Association for the Study of Pain as "pain that arises from altered nociception despite no clear evidence of actual or threatened tissue damage causing the activation of peripheral nociceptors or evidence for disease or lesion of the somatosensory system causing the pain". [2]
Pain in invertebrates is a contentious issue. Although there are numerous definitions of pain, almost all involve two key components. First, nociception is required. This is the ability to detect noxious stimuli which evokes a reflex response that moves the entire animal, or the affected part of its body, away from the source of the stimulus.