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In clinical genetics, consanguinity is defined as a union between two individuals who are related as second cousins or closer, with the inbreeding coefficient (F) equal or higher than 0.0156, where (F) represents the proportion of genetic loci at which the child of a consanguineous couple might inherit identical gene copies from both parents. [25]
The coefficient of relationship is a measure of the degree of consanguinity (or biological relationship) between two individuals. The term coefficient of relationship was defined by Sewall Wright in 1922, and was derived from his definition of the coefficient of inbreeding of 1921.
Roman civil law prohibited marriages within four degrees of consanguinity. [3] This was calculated by counting up from one prospective partner to the common ancestor, then down to the other prospective partner. [4] The first prohibited degree of consanguinity was a parent-child relationship while a second degree would be a sibling relationship.
The Fourth Lateran Council removed the second type of affinity rule and the new axiom became: "affinity does not beget affinity", which is the principle followed in the modern Catholic Church. [8] It also limited both affinity and consanguinity prohibitions to the fourth degree, but retained the same method of calculating, counting back to a ...
Consanguinity is practiced regardless of religious influences and is a result of cultural, historical, regional, and socio-economic factors. [2] [6] A greater number of consanguineous marriages are observed in rural areas compared to urban areas within the same region. This is attributed to the tendency of individuals in rural areas to marry at ...
As aunt/uncle and niece/nephew are separated by one generation, they are an example of a second-degree relationship. Unless related by marriage, they are 25% or more related by blood if the aunt/uncle is a full sibling of one of the parents, or 12.5% if they are a half-sibling .
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The table shown in the article is a table of relationships, not a table of consanguinity. A table of consanguinity shows the degree of relationship between two individuals, not just the name of their relationship to one another. For example, a person is related in the second degree to his/her grandchildren.