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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  3. Corticosteroid - Wikipedia

    en.wikipedia.org/wiki/Corticosteroid

    Synthetic pharmaceutical drugs with corticosteroid-like effects are used in a variety of conditions, ranging from hematological neoplasms [3] to brain tumors or skin diseases. Dexamethasone and its derivatives are almost pure glucocorticoids, while prednisone and its derivatives have some mineralocorticoid action in addition to the ...

  4. Direct thrombin inhibitor - Wikipedia

    en.wikipedia.org/wiki/Direct_thrombin_inhibitor

    Ximelagatran showed good efficacy compared with warfarin in several trials in prevention and treatment of deep vein thrombosis and as thromboprophylaxis in atrial fibrillation. [1] Development was stopped by manufacturer AstraZeneca , however, because of reports of liver enzyme derangements and liver failure .

  5. Coumarin derivatives - Wikipedia

    en.wikipedia.org/wiki/Coumarin_derivatives

    Warfarin – a coumarin – with brand name, Coumadin, is a prescription drug used as an anticoagulant to inhibit formation of blood clots, and so is a therapy for deep vein thrombosis and pulmonary embolism. [9] [10] [11] It may be used to prevent recurrent blood clot formation from atrial fibrillation, thrombotic stroke, and transient ...

  6. Prothrombin time - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_time

    The normal range for a healthy person not using warfarin is 0.8–1.2, and for people on warfarin therapy an INR of 2.0–3.0 is usually targeted, although the target INR may be higher in particular situations, such as for those with a mechanical heart valve. If the INR is outside the target range, a high INR indicates a higher risk of bleeding ...

  7. CHA2DS2–VASc score - Wikipedia

    en.wikipedia.org/wiki/CHA2DS2–VASc_score

    The European Society of Cardiology (ESC), [21] and National Institute for Health and Care Excellence (NICE) [23] guidelines recommend that if the patient has a CHA 2 DS 2-VASc score of 2 and above, oral anticoagulation therapy (OAC) with a vitamin K antagonist (VKA, e.g. warfarin with target INR of 2-3) or one of the direct oral anticoagulant ...

  8. Steroid-induced osteoporosis - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_osteoporosis

    The synthetic glucocorticoid prescription drug prednisone is a main candidate after prolonged intake. Bisphosphonates are beneficial in reducing the risk of vertebral fractures. [ 1 ] Some professional guidelines recommend prophylactic calcium and vitamin D supplementation in patients who take the equivalent of more than 30 mg hydrocortisone (7 ...

  9. Steroid-induced diabetes - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_diabetes

    Glycemic control can be impacted by other immunosuppressive medications through different mechanisms, which could complicate the effects of glucocorticoid therapy. [1] By inhibiting the production of insulin , calcineurin inhibitors , especially tacrolimus , are used in transplant patients, which increases their risk of developing glucose ...