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  2. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Cancer gene therapy was introduced in 1992/93 (Trojan et al. 1993). [167] The treatment of glioblastoma multiforme, the malignant brain tumor whose outcome is always fatal, was done using a vector expressing antisense IGF-I RNA (clinical trial approved by NIH protocol no.1602 24 November 1993, [168] and by the FDA in 1994). This therapy also ...

  3. Otoferlin - Wikipedia

    en.wikipedia.org/wiki/Otoferlin

    Mutations in the gene encoding otoferlin are a cause of a neurosensory nonsyndromic recessive deafness, DFNB9.The diagnosis is identified by molecular genetic testing.. In October 2023 two small clinical trials for a gene therapy restoring the defective Otoferlin via an adeno-associated virus (AAVs) have been announced.

  4. Oncomouse - Wikipedia

    en.wikipedia.org/wiki/Oncomouse

    The OncoMouse or Harvard mouse is a type of laboratory mouse (Mus musculus) that has been genetically modified using modifications designed by Philip Leder and Timothy A Stewart [1] of Harvard University to carry a specific gene called an activated oncogene (v-Ha-ras under the control of the mouse mammary tumor virus promoter).

  5. Gene therapy helps restore hearing in children with ... - AOL

    www.aol.com/gene-therapy-helps-restore-hearing...

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  6. List of gene therapies - Wikipedia

    en.wikipedia.org/wiki/List_of_gene_therapies

    Nadofaragene firadenovec (Adstiladrin): treatment for bladder cancer [13] Obecabtagene autoleucel (Aucatzyl): treatment of acute lymphoblastic leukemia [14] [15] Onasemnogene abeparvovec (Zolgensma): AAV-based treatment for spinal muscular atrophy [16] Strimvelis: treatment for adenosine deaminase deficiency (ADA-SCID)

  7. Experimental gene therapy allows kids with inherited deafness ...

    www.aol.com/news/experimental-gene-therapy...

    Gene therapy has allowed several children born with inherited deafness to hear. On Tuesday, the Children's Hospital of Philadelphia announced similar improvements in an 11-year-old boy treated there.

  8. Veterinary oncology - Wikipedia

    en.wikipedia.org/wiki/Veterinary_oncology

    Veterinary oncology is a subspecialty of veterinary medicine that deals with cancer diagnosis and treatment in animals. Cancer is a major cause of death in pet animals. In one study, 45% of the dogs that reached 10 years of age or older died of cancer. [1]

  9. Gene therapy restores hearing in five of six deaf children in ...

    www.aol.com/news/gene-therapy-restores-hearing...

    An experimental gene therapy being developed by a Chinese company restored hearing in children with congenital deafness, researchers working on a clinical trial reported on Wednesday, adding to ...