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2. 5-Hydroxytryptophan - Wikipedia

   en.wikipedia.org/wiki/5-Hydroxytryptophan

   5-HTP is produced from the amino acid tryptophan through the action of the enzyme tryptophan hydroxylase. Tryptophan hydroxylase is one of the biopterin-dependent aromatic amino acid hydroxylases. Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. [1]

3. Oxitriptan - Wikipedia

   en.wikipedia.org/wiki/Oxitriptan

   5-HTP is rapidly absorbed with a t max of ≈1.5 h, and rapidly eliminated with a half-life of ≈1.5 – 2 h. Co-administration of a decarboxylase inhibitor (e.g., carbidopa, benserazide ) doubles the half-life of 5-HTP to ≈ 3 – 4 h , [ 37 ] [ 34 ] and enhances exposure several-fold, depending on the dosing regimen.

4. Modified-release dosage - Wikipedia

   en.wikipedia.org/wiki/Time_release_drug

   Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage).

5. α-Methyl-5-hydroxytryptophan - Wikipedia

   en.wikipedia.org/wiki/Α-methyl-5-hydroxytryptophan

   α-Methyl-5-hydroxytryptophan (α-Me-5-HTP) is a synthetic tryptamine derivative, an artificial amino acid, and a prodrug of α-methylserotonin. [ 1 ] [ 2 ] It is the α- methylated derivative of 5-hydroxytryptophan (5-HTP), while αMS is the α-methylated analogue of serotonin .

6. Melatonin - Wikipedia

   en.wikipedia.org/wiki/Melatonin

   The initial step in the melatonin biosynthesis pathway is the hydroxylation of L-tryptophan's indole ring by the enzyme tryptophan hydroxylase, resulting in the formation of 5-hydroxytryptophan (5-HTP). Subsequently, 5-HTP undergoes decarboxylation, facilitated by pyridoxal phosphate and the enzyme 5-hydroxytryptophan decarboxylase, yielding ...

7. Transdermal patch - Wikipedia

   en.wikipedia.org/wiki/Transdermal_patch

   A 21mg dose Nicoderm CQ patch applied to the left arm Contraceptive patch Clonidine tablets and transdermal patch A transdermal patch which delivers medication is applied to the skin in a medical setting. The patch is labelled with the time and date of administration as well as the administrator's initials. Microneedle patch size comparison [1]