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Trametinib, sold under the brand name Mekinist among others, is an anticancer medication used for the treatment of melanoma [4] [5] and glioma. [ 6 ] [ 7 ] It is a MEK inhibitor drug with anti-cancer activity. [ 8 ]
Dabrafenib is indicated as a single agent for the treatment of people with unresectable or metastatic melanoma with BRAF V600E mutation. [2] Dabrafenib is indicated, in combination with trametinib, for BRAF V600E-positive unresectable or metastatic melanoma, metastatic non-small cell lung cancer, metastatic anaplastic thyroid cancer, and unresectable or metastatic solid tumors.
A phase III trial (vs dacarbazine) in patients with previously untreated metastatic melanoma showed an improved rates of overall and progression-free survival. [18] In June 2011, positive results were reported from the phase III BRIM3 BRAF-mutation melanoma study. [19] The BRIM3 trial reported good updated results in 2012. [20]
Pack water, a weapon, and some freakin’ sunscreen: Here are the 15 best survival movies ever made, including “Captain Phillips,” “127 Hours,” “A Quiet Place,” The Martian,” and ...
The survival film is a film genre in which one or more characters make an effort at physical survival. [1] The genre focuses on characters' life-or-death struggles ...
Based on the New York Times best-selling book Ice Bound: A Doctor's Incredible Battle for Survival at the South Pole, the movie tells the story of how, in 1999, 46-year-old physician Nielsen decides to leave Ohio and spend a year at the Amundsen–Scott South Pole Station on Antarctica, one of the most remote and perilous places on Earth.
Survival films by decade (6 C) D. Films about survivors of disasters (1 C, 4 P) P. Films based on Patrol (novel) (5 P) Post-apocalyptic films (2 C, 28 P) S.
This is a list of films and miniseries that are based on actual events. All films on this list are from American production unless indicated otherwise.. True story films [1] gained popularity in the late 1980s and early 1990s, with the production of films based on actual events that first aired on CBS, ABC, and NBC.