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Trichorrhexis nodosa is a defect in the hair shaft characterized by thickening or weak points (nodes) that cause the hair to break off easily. [ 2 ] [ 3 ] : 636 This group of conditions contributes to the appearance of hair loss , lack of growth, and damaged-looking hair.
In Uncombable Hair Syndrome mutations in TCHH, PADI3, or TGM3 result in improper cross-linking and the resulting irregular shape of the hair shaft. [citation needed] The particular defect in TCHH as a structural component of hair may be a defect of deimination. Deimination converts the amino acid arginine to the amino acid citrulline.
Perhaps the most well-known condition to cause hair loss is alopecia, which, Massick explains, “causes your own immune system to attack the hair follicles [so that] the hairs just fall out ...
But in some cases, external factors — like stress — can affect hair, causing everything from thinning hair and a wider part, to a receding hairline, hair falling out in clumps or even patches ...
Symptoms of Hair Loss in Women. Now you know some common causes of hair loss in women, but if you’re still wondering if you’re dealing with normal hair shedding or actual hair loss, we got you ...
In alopecia areata, a hair follicle is attacked by the immune system. T-cells swarm the roots, killing the follicle. This causes the hair to fall out and parts of the head to become bald. Alopecia areata is thought to be a systemic autoimmune disorder in which the body attacks its own anagen hair follicles and suppresses or stops hair growth. [22]
At the end of the resting phase, the hair falls out (exogen) and a new hair starts growing in the follicle, beginning the cycle again. Normally, about 40 (0–78 in men) hairs reach the end of their resting phase each day and fall out. [28] When more than 100 hairs fall out per day, clinical hair loss (telogen effluvium) may occur.
Hair diseases are illnesses that impact the persistence and regular growth of hair. Types of hair diseases include folliculitis , hirsutism , hypertrichosis , hypotrichosis ( alopecia ), Menkes kinky hair syndrome , monilethrix , and piedra .