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Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024 ... Stroke and traumatic brain injury lead to cell death, ...
Traumatic brain injury (TBI) can deform the brain tissue, leading to necrosis primary damage which can then cascade and activate secondary damage such as excitotoxicity, inflammation, ischemia, and the breakdown of the blood-brain-barrier. Damage can escalate and eventually lead to apoptosis or cell death. Current treatments focus on preventing ...
Endogenous regeneration in the brain is the ability of cells to engage in the repair and regeneration process. While the brain has a limited capacity for regeneration, endogenous neural stem cells, as well as numerous pro-regenerative molecules, can participate in replacing and repairing damaged or diseased neurons and glial cells.
Stem cells have a tendency to migrate out of the injury site to other sections of the brain, thus the therapy is not as effective as it could be as when the cells stay at the injury site. Additionally, the delivery of stem cells and other morphogens to the site of injury can cause more harm than good if they induce tumorigenesis, inflammation ...
Diseases and conditions where stem cell treatment is being investigated include: Diabetes [125] Androgenic Alopecia and hair loss [126] [127] Rheumatoid arthritis [125] Parkinson's disease [125] Alzheimer's disease [125] Respiratory disease [128] Osteoarthritis [125] Stroke and traumatic brain injury repair [129] Learning disability due to ...
Having a traumatic brain injury (TBI). One moment I was me, then suddenly, was robbed of my own soul. Ruined my hopes, dreams, and motivation at age 26 in a mountain biking accident. 43, alone ...
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