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In physiology, body water is the water content of an animal body that is contained in the tissues, the blood, the bones and elsewhere. The percentages of body water contained in various fluid compartments add up to total body water (TBW). This water makes up a significant fraction of the human body, both by weight and by volume.
V – volume of distribution of urea, approximately equal to patient's total body water; In the context of hemodialysis, Kt/V is a pseudo-dimensionless number; it is dependent on the pre- and post-dialysis concentration (see below). It is not the product of K and t divided by V, as would be the case in a true dimensionless number. [1]
A V D greater than the total volume of body water (approximately 42 liters in humans [5]) is possible, and would indicate that the drug is highly distributed into tissue. In other words, the volume of distribution is smaller in the drug staying in the plasma than that of a drug that is widely distributed in tissues.
In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is usually slightly lower in women (52–55%). [2] [3] The exact percentage of fluid relative to body weight is inversely proportional to the percentage of body fat. A lean 70 kg (150 lb) man, for example, has about 42 (42–47) liters of water ...
According to the Institute of Medicine, men are recommended to take in 125 ounces (3.7 liters) of total fluid from beverages and food each day, while women are advised to consume 91 ounces (2.7 ...
The adult human body averages ~53% water. [7] This varies substantially by age, sex, and adiposity. In a large sample of adults of all ages and both sexes, the figure for water fraction by weight was found to be 48 ±6% for females and 58 ±8% water for males. [8]
Total body water in healthy adults is about 50–60% (range 45 to 75%) of total body weight; [1] women and the obese typically have a lower percentage than lean men. [2] Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells. [3]
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