Search results
Results from the WOW.Com Content Network
In general, contraindications to antipsychotic switching are cases in which the risk of switching outweighs the potential benefit. Contraindications to antipsychotic switching include effective treatment of an acute psychotic episode, patients stable on a LAI antipsychotic with a history of poor adherence, and stable patients with a history of self-injurious behavior, violent behavior, or ...
Lamotrigine is metabolized predominantly by glucuronic acid conjugation. Its major metabolite is an inactive 2-n-glucuronide conjugate. [82] Lamotrigine has fewer drug interactions than many anticonvulsant drugs, although pharmacokinetic interactions with carbamazepine, phenytoin and other hepatic enzyme-inducing medications may shorten half ...
Carbamazepine was the first anti-convulsant shown to be effective for treating bipolar mania. It has not been extensively studied in bipolar depression. [2] It is generally considered a second-line agent due to its side effect profile. [2] Lamotrigine is considered a first-line agent for the treatment of bipolar depression.
Switching directly is usually only a safe option for switching between certain SSRIs and SNRIs with short half-lives, as these medications are less likely to cause drug interactions or unwanted ...
Similarly, children exposed lamotrigine or phenytoin in the womb do not seem to differ in their skills compared to those who were exposed to carbamazepine. [ 96 ] There is inadequate evidence to determine if newborns of women with epilepsy taking anticonvulsants have a substantially increased risk of hemorrhagic disease of the newborn .
Lamotrigine can cause Stevens–Johnson syndrome, a very rare but potentially fatal skin condition. [ 7 ] Carbamazepine – FDA approved for the treatment of acute manic or mixed (i.e., both depressed and manic mood features) episodes in people with bipolar disorder type I. [ 9 ] Carbamazepine can rarely cause a dangerous decrease in ...
Tegretol (carbamazepine) – an anticonvulsant used as a mood stabilizer; Trilafon (perphenazine)- an antipsychotic used to treat schizophrenia; Tranxene, Novo-Clopate (clorazepate) – a benzodiazepine with anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties
Licarbazepine is a voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects that is related to oxcarbazepine. [1] It is an active metabolite of oxcarbazepine.