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Alka-Seltzer is an effervescent antacid and pain reliever owned by Bayer since 1978. First marketed by the Dr. Miles Medicine Company of Elkhart, Indiana , United States , Alka-Seltzer contains three active ingredients: aspirin (acetylsalicylic acid or ASA), sodium bicarbonate , and anhydrous citric acid . [ 1 ]
In the process, Bayer also acquired products such as Alka-Seltzer, Flintstones Vitamins, One-a-Day, Bactine, [11] S.O.S Soap Pads, and Worthington Foods. Bayer continued to operate Miles Laboratories and developed many drugs based upon biological extracts, such as Kogenate , Gamimune-N and other immunoglobulins , and Trasylol , as well as ...
Noted over-the-counter Bayer products include Aleve, Bayer Aspirin, Alka-Seltzer, Phillip's Laxatives, Bactine, One-A-Day Vitamins, Flintstone Vitamins, and Midol.The company also markets prescription medications, animal medications, and diagnostic and medical testing equipment.
Bayer has owned Alka-Seltzer since 1978. In 1978, Bayer purchased Miles Laboratories and its subsidiaries Miles Canada and Cutter Laboratories, acquiring along with them a variety of product lines including Alka-Seltzer, Flintstones vitamins and One-A-Day vitamins, and Cutter insect repellent. [65]
Metal chelation is responsible for some of these interactions (e.g. fluoroquinolones, tetracyclines), leading to decreased absorption of the chelated drug. Some interactions may be due to the pH increase observed in the stomach following antacid ingestion , leading to increased absorption of weak acids, and decreased absorption of weak bases.
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A study of a group with a mean dosage of aspirin of 270 mg per day estimated an average absolute risk increase in intracerebral hemorrhage (ICH) of 12 events per 10,000 persons. [218] In comparison, the estimated absolute risk reduction in myocardial infarction was 137 events per 10,000 persons, and a reduction of 39 events per 10,000 persons ...
Another non-aspirin-based variant, Alka-Seltzer Gold, was later released. Since 1978 Alka-Seltzer has been owned by Bayer Schering Pharma AG, Germany. [1] The name "Alka-Seltzer" has been extended to incorporate an entire line of medications sold over the counter and taken by means of rapidly dissolving tablets that form a carbonated solution ...