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Adhesion is the tendency of dissimilar particles or surfaces to cling to one another. (Cohesion refers to the tendency of similar or identical particles and surfaces to cling to one another.) The forces that cause adhesion and cohesion can be divided into several types.
Cell junctions [1] or junctional complexes are a class of cellular structures consisting of multiprotein complexes that provide contact or adhesion between neighboring cells or between a cell and the extracellular matrix in animals. [2] They also maintain the paracellular barrier of epithelia and control paracellular transport. Cell junctions ...
Schematic of cell adhesion. Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released ...
The inner dense plaque, also about 15–20 nm in length, contains the C-terminus end of desmoplakin and their attachment to keratin intermediate filaments. Desmoplakin is the most abundant part of the desmosome, [7] as it operates as the mediator between the cadherin proteins in the plasma membrane and the keratin filaments. Desmoplakin has two ...
The process is highly regulated by cell adhesion molecules, particularly, the addressin also known as MADCAM1. This antigen is known for its role in tissue-specific adhesion of lymphocytes to high endothelium venules. [23] Through these interactions they play a crucial role in orchestrating circulating lymphocytes.
Cohesion, along with adhesion (attraction between unlike molecules), helps explain phenomena such as meniscus, surface tension and capillary action. Mercury in a glass flask is a good example of the effects of the ratio between cohesive and adhesive forces.
In cell biology, adherens junctions (or zonula adherens, intermediate junction, or "belt desmosome" [1]) are protein complexes that occur at cell–cell junctions and cell–matrix junctions in epithelial and endothelial tissues, [2] usually more basal than tight junctions.
The relationship between forces on focal adhesions and their compositional maturation, however, remains unclear. For instance, preventing focal adhesion maturation by inhibiting myosin activity or stress fiber assembly does not prevent forces sustained by focal adhesions, nor does it prevent cells from migrating.