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Gas gangrene (also known as clostridial myonecrosis [1]) is a bacterial infection that produces tissue gas in gangrene. This deadly form of gangrene usually is caused by Clostridium perfringens bacteria. About 1,000 cases of gas gangrene are reported yearly in the United States. [2] Myonecrosis is a condition of necrotic damage, specific to ...
Clostridium perfringens is a common cause of food poisoning in the United States. C. perfringens produces spores, and when these spores are consumed, they produce a toxin that causes diarrhea. Foods cooked in large batches and held at unsafe temperatures (between 40 °F and 140 °F) are the source of C. perfringens food poisoning outbreaks.
This toxin has been shown to be the key virulence factor in infection with C. perfringens; the bacterium is unable to cause disease without this toxin. [1] Further, vaccination against the alpha toxin toxoid protects mice against C. perfringens gas gangrene. [2]
Clostridium perfringens causes a wide range of symptoms, from food poisoning to cellulitis, fasciitis, necrotic enteritis and gas gangrene. [16] [17] Clostridium tetani causes tetanus. Several more pathogenic species, that were previously described in Clostridium, have been found to belong to other genera. [6]
Clostridium septicum [1] is a gram positive, spore forming, obligate anaerobic bacterium. Clostridium septicum can cause gas gangrene, but unlike other Clostridium species like Clostridium perfringens, no trauma is necessary at the site of the infection. It is thought that the infection is established by hematogenous spread from the ...
Welch's research was principally in bacteriology, and he is the discoverer of the organism that causes gas gangrene. It was named Clostridium welchii in recognition of that fact, but now the organism usually is designated as Clostridium perfringens.
Clostridium perfringens: Food poisoning by Clostridium perfringens: Stool test Supportive care No multiple Free-living amebic infection: No Fusobacterium species Fusobacterium infection No usually Clostridium perfringens; other Clostridium species Gas gangrene (Clostridial myonecrosis) No Geotrichum candidum: Geotrichosis: No PRNP
Main article: Human parasite Endoparasites Protozoan organisms Common name of organism or disease Latin name (sorted) Body parts affected Diagnostic specimen Prevalence Source/Transmission (Reservoir/Vector) Granulomatous amoebic encephalitis and Acanthamoeba keratitis (eye infection) Acanthamoeba spp. eye, brain, skin culture worldwide contact lenses cleaned with contaminated tap water ...