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Normally, HFE facilitates the binding of transferrin, which is iron's carrier protein in the blood. Transferrin levels are typically elevated at times of iron depletion (low ferritin stimulates the release of transferrin from the liver). When transferrin is high, HFE works to increase the intestinal release of iron into the blood.
Majority of the cases of hemochromatosis are caused by mutations in the HFE (Homeostatic Iron Regulator) gene. [17] Type 3 HH is characterized by compound heterozygote mutations in both transferrin receptor 2 (TFR2) and HFE, i.e. a single mutation in each gene. HFE is located on chromosome 6 and TFR2 is located on chromosome 7.
They are sometimes applied as blends such as HFE 7100, which is a mixture of methyl nonafluorobutyl ether (methoxyperfluorobutane) and methyl nonafluoroisobutyl ether. [ 2 ] 3M produces hydrofluoroether compounds under the names Novec 7000, 7100, 7200, 7300, 7500, and 7700 as liquid coolants for many applications including full immersion ...
HFE. The HFE H63D is a single-nucleotide polymorphism in the HFE gene (c.187C>G, rs1799945), which results in the substitution of a histidine for an aspartic acid at amino acid position 63 of the HFE protein (p.His63Asp). HFE participates in the regulation of iron absorption. [1] [2] [3]
The Standard Carrier Alpha Code (SCAC) is a privately controlled US code used to identify vessel operating common carriers (VOCC). It is typically two to four letters long. It is typically two to four letters long.
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Human homeostatic iron regulator protein, also known as the HFE protein (High FE2+), is a transmembrane protein that in humans is encoded by the HFE gene. The HFE gene is located on short arm of chromosome 6 at location 6p22.2 [ 5 ]
This list is only of aircraft that have an article, indexed by aircraft registration "tail number" (civil registration or military serial number). The list includes aircraft that are notable either as an individual aircraft or have been involved in a notable accident or incident or are linked to a person notable enough to have a stand-alone Wikipedia article.