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Common adverse effects include diarrhea, nausea, and abdominal pain. [16] It has a small risk of causing low blood sugar. [16] High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. [23] [24] Metformin is a biguanide anti-hyperglycemic agent. [16]
Prepare for potential side effects. Taking metformin may cause unpleasant side effects like diarrhea, nausea, and an upset stomach. Taking it with food can reduce the risk.
2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.
Metformin is a prescription medication used to treat high blood sugar in those with type 2 diabetes who are resistant to the effects of insulin. It’s in a class of drugs known as biguanides.
Higher risk of gastrointestinal side effects Due to the risk of potentially fatal lactic acidosis , contraindicated in people with shock ; with acute or chronic, moderate or severe kidney disease or at risk for impaired kidney function from intravenous dye ; and with acute or chronic metabolic acidosis
In the United States, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes. [5] [6]In the European Union, sitagliptin/metformin is indicated as an adjunct to diet and exercise to improve glycemic control in people with type 2 diabetes; in combination with a sulfonylurea as an adjunct to diet and exercise "in people ...
It is believed that malabsorption of vitamin B 12 in diabetic patients, is due to individuals taking metformin therapy (an insulin sensitizer used for treating type 2 diabetes). [81] Furthermore, obese individuals with type 2 diabetes are likely to develop gastroesophageal reflux disease, [ 82 ] and take proton pump inhibitors, which further ...
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