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Peptide fragmentation notation using the scheme of Roepstorff and Fohlman (1984). [5] A notation has been developed for indicating peptide fragments that arise from a tandem mass spectrum. [5] Peptide fragment ions are indicated by a, b, or c if the charge is retained on the N-terminus and by x, y or z if the charge is maintained on the C ...
Pictured is an L-peptide (1) fragment with the sequence Asp-Val-Ser and the D-peptide Asp-Val-Ser (2) shown from C-terminus to N-terminus. When placed in a nonchiral solvent like water, D-peptides, as well as the larger polypeptide D-proteins, have similar but mirrored properties to the L-peptides and L-proteins with identical sequences.
Print/export Download as PDF; Printable version; In other projects ... Peptide sequences (12 P) Spider toxins (42 P) T. Tetradecapeptides (2 P) Tetrapeptides (17 P)
In mass spectrometry, de novo peptide sequencing is the method in which a peptide amino acid sequence is determined from tandem mass spectrometry. Knowing the amino acid sequence of peptides from a protein digest is essential for studying the biological function of the protein. In the old days, this was accomplished by the Edman degradation ...
The N-terminus is the first part of the protein that exits the ribosome during protein biosynthesis. It often contains signal peptide sequences, "intracellular postal codes" that direct delivery of the protein to the proper organelle. The signal peptide is typically removed at the destination by a signal peptidase. The N-terminal amino acid of ...
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Protein primary structure is the linear sequence of amino acids in a peptide or protein. [1] By convention, the primary structure of a protein is reported starting from the amino -terminal (N) end to the carboxyl -terminal (C) end.
Protein tandem repeats can be either detected from sequence or annotated from structure. Specialized methods were built for the identification of repeat proteins. [13] Sequence-based strategies, based on homology search [14] or domain assignment, [15] [16] mostly underestimate TRs due to the presence of highly degenerate repeat units. [17]
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