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Sodium phenylbutyrate, sold under the brand name Buphenyl among others, is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. [7] The compound is used to treat urea cycle disorders , because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen.
Sodium butyrate is a compound with formula Na(C 3 H 7 COO). It is the sodium salt of butyric acid . It has various effects on cultured mammalian cells including inhibition of proliferation , induction of differentiation and induction or repression of gene expression. [ 1 ]
Sodium phenylbutyrate is a chemical chaperone that helps proteins maintain their normal conformation, preventing aggregation that may lead to cell death. [6] Ursodoxicoltaurine improves mitochondrial energy production.
the aliphatic acid compounds such as Sodium phenylbutyrate and valproic acid. As of 2007, "second-generation" HDIs included the hydroxamic acids : trichostatin A , vorinostat (SAHA), belinostat (PXD101), resminostat , abexinostat , givinostat , LAQ824 , ivaltinostat , nanatinostat and panobinostat (LBH589); and the benzamides : entinostat (MS ...
Sodium butyrate; This page was last edited on 12 July 2024, at 00:43 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 ...
This page was last edited on 12 January 2024, at 05:03 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.
Glycerol phenylbutyrate, sold under the brand name Ravicti, is a medication used in the treatment of certain inborn urea cycle disorders. The medication works by preventing the harmful buildup of ammonia in the body. [ 3 ]
Phenylacetylglutamine is the primary metabolite of the degradation of phenylacetate when in the presence of glutamine in the liver. It is also produced in higher concentrations in the body through the metabolic degradation pathway of the pharmaceutical compounds sodium phenylbutyrate, glycerol phenylbutyrate, and sodium phenylacetate, considered more toxic, that are used as treatments for the ...
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