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Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
A vitamin B12 deficiency can be caused by a gastrointestinal disorder or a lack of B12 in your diet. Signs of a B12 deficiency include weakness, fatigue, and tingling or numbness in the hands and ...
First, have your health care provider run blood tests to see if you truly have a B12 deficiency. If you do, the only way to treat it is to consume more B12, either through food, supplements or ...
Angular cheilitis – a fissure running in the corner of the mouth with reddened, irritated facial skin adjacent. A fairly mild case of angular cheilitis extending onto the facial skin in a young person (affected area is within the black oval). Angular cheilitis is a fairly non specific term which describes the presence of an inflammatory ...
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
The Schilling test distinguished PA from other forms of B 12 deficiency, [50] specifically, from Imerslund–Gräsbeck syndrome, a B 12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. [1] Vitamin B12 deficiency is also prevalent in patients having Crohn's disease (CD) so it should be differentiated. [62]