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  2. BRCA mutation - Wikipedia

    en.wikipedia.org/wiki/BRCA_mutation

    Only 5–10% of breast cancer cases in women are attributed to BRCA1 and BRCA2 mutations (with BRCA1 mutations being slightly more common than BRCA2 mutations), but the impact on women with the gene mutation is more profound. [2] Women with harmful mutations in either BRCA1 or BRCA2 have a risk of breast cancer that is about five times the ...

  3. Guidelines say more women may need breast cancer gene test - AOL

    www.aol.com/news/2019-08-26-guidelines-say-more...

    More women may benefit from gene testing for hereditary breast or ovarian cancer, especially if they've already survived cancer once, an influential health group recommended Tuesday.

  4. BRCA2 - Wikipedia

    en.wikipedia.org/wiki/BRCA2

    An approximately 50-amino acid segment that contains four short helices (alpha 2 to alpha 4), meanders around the surface of the core structure. In BRCA2, the alpha 9 and alpha 10 helices pack with the BRCA2 OB1 domain through van der Waals contacts involving hydrophobic and aromatic residues, and also through side-chain and backbone hydrogen ...

  5. Breast cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer

    This is an accepted version of this page This is the latest accepted revision, reviewed on 29 January 2025. Cancer that originates in mammary glands Medical condition Breast cancer An illustration of breast cancer Specialty Surgical Oncology Symptoms A lump in a breast, a change in breast shape, dimpling of the skin, fluid from the nipple, a newly inverted nipple, a red scaly patch of skin on ...

  6. New Breast Cancer Screening Guidelines for Women 40 to 74 ...

    www.aol.com/lifestyle/breast-cancer-screening...

    The U.S. Preventative Services Task Force (USPSTF) has finalized new breast cancer screening guidelines for women ages 40 to 74.

  7. Living with BRCA2 mutation, she fought 2 cancers: 'Little ...

    www.aol.com/news/living-brca2-mutation-she...

    A BRCA2 gene mutation is associated with breast cancer, but it can also raise the risk of other cancers. Woman shares story of her pancreatic cancer diagnosis.

  8. Ovarian cancer - Wikipedia

    en.wikipedia.org/wiki/Ovarian_cancer

    Women with hereditary nonpolyposis colon cancer (Lynch syndrome), and those with BRCA-1 and BRCA-2 genetic abnormalities are at increased risk. The major genetic risk factor for ovarian cancer is a mutation in BRCA1 or BRCA2 genes, or in DNA mismatch repair genes, which is present in 10% of ovarian

  9. Screen women for breast cancer at 40, instead of 50, new ...

    www.aol.com/news/breast-cancer-guidelines-start...

    Women over 40 should get breast cancer screenings every other year, according to the U.S. Preventive Services Task Force. But some doctors think scans should be annual.