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Xerostomia, also known as dry mouth, is a subjective complaint of dryness in the mouth, which may be associated with a change in the composition of saliva, or reduced salivary flow, or have no identifiable cause. [1] This symptom is very common and is often seen as a side effect of many types of medication.
Xerostomia itself has many possible causes, but commonly the cause may be side effects of medications, or conditions such as Sjögren's syndrome. Conversely, conditions which cause drooling or sialorrhoea (excessive salivation) can cause angular cheilitis by creating a constant wet environment in the corners of the mouth.
Known side effects include nausea, vomiting, diarrhea, excessive sweating, rash, headache, runny nose, cough, drowsiness, hot flashes, blurred vision, and difficulty sleeping. [3] Contraindications include asthma and angle closure glaucoma. [citation needed]
These buccal tablets are administered for the treatment of severe nausea and vomiting associated with migraine, [13] [14] as well as managed in symptoms of schizophrenia. Side effects typically seen in patients using prochlorperazine maleate tablets include drowsiness, blurred vision, dry mouth, and headache.
Hypersalivation can contribute to drooling if there is an inability to keep the mouth closed or difficulty in swallowing (dysphagia) the excess saliva, which can lead to excessive spitting. Hypersalivation also often precedes emesis (vomiting), where it accompanies nausea (a feeling of needing to vomit).
Bradycardia; Hypertension (high blood pressure); Allergic reactions (e.g. dyspnoea (shortness of breath), bronchospasm, wheezing, angioneurotic oedema) Anaphylaxis; Changes in appetite
By mouth it is used for dry mouth as a result of Sjögren syndrome or radiation therapy. [9] Common side effects of the eye drops include irritation of the eye, increased tearing, headache, and blurry vision. [1] Other side effects include allergic reactions and retinal detachment. [1] Use is generally not recommended during pregnancy. [10]
Because medications have been linked to approximately 22% to 28% of all cases of dysgeusia, researching a treatment for this particular cause has been important. [39] Xerostomia, or a decrease in saliva flow, can be a side effect of many drugs, which, in turn, can lead to the development of taste disturbances such as dysgeusia. [39]
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