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The causes of Alzheimer's disease remain poorly understood. [16] There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an allele of apolipoprotein E. [17] [18] Other risk factors include a history of head injury, clinical depression, and high blood pressure. [1]
Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia; it usually occurs in old age. Familial Alzheimer's disease (FAD or EOFAD for early onset) is an inherited and uncommon form of AD. Familial AD usually strikes earlier in life, defined as before the age of 65.
The prevention of dementia involves reducing the number of risk factors for the development of dementia, and is a global health priority needing a global response. [1] [2] Initiatives include the establishment of the International Research Network on Dementia Prevention (IRNDP) [3] which aims to link researchers in this field globally, and the establishment of the Global Dementia Observatory ...
As MCI may represent a prodromal state to clinical Alzheimer's dementia, treatments for Alzheimer's disease could potentially be useful. [26] Of these, rivastigmine failed to stop or slow progression to Alzheimer's disease or to improve cognitive function for individuals with mild cognitive impairment; [ 27 ] donepezil showed only minor, short ...
The Mayo Clinic diet was created by weight management practitioners at the Mayo Clinic and was designed as a lifestyle change program to promote gradual and sustained weight loss, says Melissa ...
“Alzheimer’s disease has a long pre-symptomatic period; Alzheimer’s-related changes take place in the brain 10, 15, even 20 years before the onset of memory and thinking symptoms.
An estimated 6.7 million Americans ages 65 and older were living with Alzheimer’s in 2023, according to the Alzheimer’s Association. The number is projected to increase to 13.8 million by 2060.
The treatment will depend on the cause of memory loss, but various drugs to treat Alzheimer's disease have been suggested in recent years. There are four drugs currently approved by the Food and Drug Administration (FDA) for the treatment of Alzheimer's, and they all act on the cholinergic system: Donepezil, Galantamine, Rivastigmine, and ...