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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
By the early 1970s, it was appreciated that there are two main classes of GABA receptors, GABA A and GABA B and also that baclofen was an agonist of GABA B receptors. Gabapentin was designed, synthesized and tested in mice by researchers at the pharmaceutical company Goedecke AG in Freiburg, Germany (a subsidiary of Parke-Davis).
Most people want to live a long, healthy life, and there’s plenty of research dedicated to achieving that goal.While science has found that doing things like eating a plant-based diet and ...
The current Philippine military ranks are inspired partially by the first military insignia used by the military forces during the Philippine Revolution of 1896 and the Philippine–American War, and the insignia used by the Philippine Constabulary raised in 1902 during the final days of the Philippine–American War, which was basically the same style of insignia used by the United States ...
[2] [3] In 2012, the United Nations said the Philippines had the highest rate of methamphetamine use in East Asia, and according to a U.S. State Department report, 2.1 percent of Filipinos aged 16 to 64 use the drug [4] based on 2008 figures by the Philippines Dangerous Drugs Board. [5]
Imipramine is primarily used for the treatment of depression and certain anxiety disorders, including acute post-traumatic stress reactions. A significant amount of research regarding its efficacy on acute post-traumatic stress in children and adolescents has focused on trauma resulting from burn-injuries.
Eszopiclone, sold under the brand name Lunesta among others, is a medication used in the treatment of insomnia. [3] [4] Evidence supports slight to moderate benefit up to six months.
Meclizine, sold under the brand name Bonine, among others, is an antihistamine used to treat motion sickness and dizziness (). [3] It is taken by mouth. [3] Effects generally begin in an hour and last for up to a day.