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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
Adverse drug reaction: palmoplantar erythrodysesthesia (acral erythema) Because circulating levels of estrogen increase in both cirrhosis and pregnancy, estrogen was thought to be the main cause for the increased vascularity. More recently, nitric oxide has also been implicated in the pathogenesis of palmar erythema. [5]
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In humans, volar can also be used synonymously with palmar to refer to the underside of the palm, but plantar is used exclusively to describe the sole. These terms describe location as palmar and plantar ; For example, volar pads are those on the underside of hands or fingers; the plantar surface describes the sole of the heel, foot or toes.
The palmar plate moves in three phases during joint flexion. First, it slides back toward the hand. Next, it is lifted away from the proximal phalanx by the A3 pulley. Last, a lip on the middle phalanx rolls into a recess on the plate. If the A3 pulley is not intact, the normal three phases of motion do not occur and instead the plate crumples. [7]
The anatomy and composition of the plantar plates are similar to the palmar plates in the metacarpophalangeal (MCP) and interphalangeal joints in the hand; the proximal origin is thin but the distal insertion is stout. Due to the weight-bearing nature of the human foot, the plantar plates are exposed to extension forces not present in the human ...
Just as maps are normally oriented with north at the top, the standard body "map", or anatomical position, is that of the body standing upright, with the feet at shoulder width and parallel, toes forward. The upper limbs are held out to each side, and the palms of the hands face forward. [1] Using the standard anatomical position reduces confusion.
For palmoplantar hyperhidrosis, 20% aluminum chloride hexahydrate in absolute anhydrous ethyl alcohol () is the most effective topical treatment. [4] Other topical treatments such as potassium permanganate, tannic acid (2 to 5 percent solutions), resorcinol, boric acid, formaldehyde, methenamine, and glutaraldehyde have yielded less than desirable results.