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The CTX test measures for the presence and concentration of a crosslink peptide sequence of type I collagen, found, among other tissues, in bone. This specific peptide sequence relates to bone turnover because it is the portion that is cleaved by osteoclasts during bone resorption, and its serum levels are therefore proportional to osteoclastic ...
As osteoblasts produce osteocalcin, it is often used as a marker for the bone formation process.Higher serum osteocalcin levels have been observed to correlate relatively well with increases in bone mineral density during treatment with anabolic bone formation drugs for osteoporosis, such as teriparatide.
3569 16193 Ensembl ENSG00000136244 ENSMUSG00000025746 UniProt P05231 P08505 RefSeq (mRNA) NM_000600 NM_001318095 NM_001371096 NM_031168 NM_001314054 RefSeq (protein) NP_000591 NP_001305024 NP_001358025 NP_001300983 NP_112445 Location (UCSC) Chr 7: 22.73 – 22.73 Mb Chr 5: 30.22 – 30.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 6 (IL-6) is an interleukin that acts ...
Type 2 inflammation is a pattern of immune response. Its physiological function is to defend the body against helminths , but a dysregulation of the type 2 inflammatory response has been implicated in the pathophysiology of several diseases.
In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."
Osteoporosis is a systemic skeletal disorder characterized by low bone mass, micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk. It is the most common reason for a broken bone among the elderly. [3]
Scientists have long known that aging varies widely among individuals, influenced by genetics and lifestyle choices. Now, a new tool called CheekAge offers a simple, noninvasive way to predict ...
Positive acute-phase proteins serve (as part of the innate immune system) different physiological functions within the immune system.Some act to destroy or inhibit growth of microbes, e.g., C-reactive protein, mannose-binding protein, [3] complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin.