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Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phosphocreatine kinase, is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP).
Sigma level (σ) Area under the probability density function Process yield Process fallout (in terms of DPMO/PPM) 0.33 1 0.3085375387 30.85% 691462 0.67 2 0.6914624613 69.15% 308538 1.00 3 0.9331927987 93.32% 66807 1.33 4 0.9937903347 99.38% 6209 1.67 5 0.9997673709 99.9767% 232.6 2.00 6 0.9999966023 99.99966%
The CPK-MB test (creatine phosphokinase-MB), also known as CK-MB test, is a cardiac marker [3] used to assist diagnoses of an acute myocardial infarction, myocardial ischemia, or myocarditis. It measures the blood level of CK-MB (creatine kinase myocardial band), the bound combination of two variants (isoenzymes CKM and CKB ) of the enzyme ...
The most reliable test in the diagnosis of rhabdomyolysis is the level of creatine kinase (CK) in the blood. [5] This enzyme is released by damaged muscle, and levels above 1000 U/L (5 times the upper limit of normal (ULN)) indicate rhabdomyolysis. [5]
Test Sensitivity and specificity Approximate peak Description Troponin test: The most sensitive and specific test for myocardial damage. Because it has increased specificity compared with CK-MB, troponin is composed of 3 proteins- Troponin C, Cardic troponin I, and Cardiac troponin T. Troponin I especially has a high affinity for myocardial injury.
The process capability is a measurable property of a process to the specification, expressed as a process capability index (e.g., C pk or C pm) or as a process performance index (e.g., P pk or P pm).
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Isolated hyperCKemia is a benign [1] genetic disorder which is characterized by high levels of creatine kinase (an enzyme) in the blood, usually, levels of CK in the blood of people with this disorder are 3 to 10 times higher than average.