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Acquired asplenia occurs for several reasons: Following splenectomy due to splenic rupture from trauma or because of tumor After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura , thalassemia , spherocytosis ), in which the spleen's usual activity exacerbates ...
Without these immune functions, individuals with isolated congenital asplenia are extremely susceptible to infection. [10] Streptococcus pneumoniae is a common bacteria that affects individuals with ICAS, often causes meningitis, sepsis, and otitis media. [9]
Asplenia with cardiovascular anomalies, also known as Ivemark syndrome and right atrial isomerism, [1] is an example of a heterotaxy syndrome. These uncommon congenital disorders are characterized by defects in the heart, spleen and paired organs such as the lungs and kidneys.
Isolated congenital asplenia. Bowen–Conradi syndrome. Bowen–Conradi syndrome (BCS [38] or BWCNS [39]) is an autosomal recessive abnormality of ...
This is a list of primary immunodeficiencies (PID), which are immune deficiencies that are not secondary to another condition.. The International Union of Immunological Societies recognizes nine classes of primary immunodeficiencies, totaling approximately 430 conditions.
Situs ambiguus (from Latin 'ambiguous site'), or heterotaxy, is a rare congenital defect in which the major visceral organs are distributed abnormally within the chest and abdomen. Clinically, heterotaxy spectrum generally refers to any defect of left-right asymmetry and arrangement of the visceral organs; however, classical heterotaxy requires ...
Accessory spleens may undergo hypertrophy after splenectomy [15] Very rarely, it may cause bleeding (pictured). [16]If splenectomy is performed for conditions in which blood cells are sequestered in the spleen, failure to remove accessory spleens may result in the failure of the condition to resolve. [1]
Polysplenia is a congenital disease manifested by multiple small accessory spleens, [1] rather than a single, full-sized, normal spleen.Polysplenia sometimes occurs alone, but it is often accompanied by other developmental abnormalities.