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Myoglobin is a sensitive marker for muscle injury, making it a potential marker for heart attack in patients with chest pain. [33] However, elevated myoglobin has low specificity for acute myocardial infarction (AMI) and thus CK-MB , cardiac troponin , ECG , and clinical signs should be taken into account to make the diagnosis.
All bones possess larger or smaller foramina (openings) for the entrance of blood-vessels; these are known as the nutrient foramina, and are particularly large in the shafts of the larger long bones, where they lead into a nutrient canal, which extends into the medullary cavity. The nutrient canal (foramen) is directed away from the growing end ...
Diagram of a typical long bone showing both cortical (compact) and cancellous (spongy) bone. Haversian canals [i] (sometimes canals of Havers, osteonic canals or central canals) are a series of microscopic tubes in the outermost region of bone called cortical bone. They allow blood vessels and nerves to travel through them to supply the osteocytes.
A decrease in muscle mass may be accompanied by a smaller number and size of the muscle cells as well as lower protein content. [89] Human spaceflight, involving prolonged periods of immobilization and weightlessness is known to result in muscle weakening and atrophy resulting in a loss of as much as 30% of mass in some muscles.
Myoglobinuria, the presence of myoglobin in the urine, occurs when the level in plasma exceeds 0.5–1.5 mg/dL; once plasma levels reach 100 mg/dL, the concentration in the urine becomes sufficient for it to be visibly discolored [10] and corresponds with the destruction of about 200 grams of muscle. [18]
The number of bones varies according to the method used to derive the count. While some consider certain structures to be a single bone with multiple parts, others may see it as a single part with multiple bones. [5] There are five general classifications of bones. These are long bones, short bones, flat bones, irregular bones, and sesamoid bones.
The long bones of the human leg comprise nearly half of adult height. The other primary skeletal component of height are the vertebrae and skull. The outside of the bone consists of a layer of connective tissue called the periosteum. Additionally, the outer shell of the long bone is compact bone, then a deeper layer of cancellous bone (spongy ...
Diameter of canaliculi in human bone is approximately 200 to 900 nm. [1] In bovine tibia diameter of canaliculi was found to vary from 155 to 844 nm (average 426 nm). [ 2 ] In mice humeri it varies from 80 to 710 nm (average 259 nm), while diameter of osteocytic processes varies from 50 to 410 nm (average 104 nm).