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It is one of the preferred treatments for high blood pressure in pregnancy. [1] For other types of high blood pressure including very high blood pressure resulting in symptoms other medications are typically preferred. [1] It can be given by mouth or injection into a vein. [1] Onset of effects is around 5 hours and they last about a day. [1]
The positive charge on most metals can interact with the negative charge of the phosphate backbone of DNA. Some drugs developed that include metals interact directly with other metals already present in protein active sites, while other drugs can use metals to interact with amino acids with the highest reduction potential. [4] Figure 2.
The point at which delivery becomes recommended depends on how severe the pre-eclampsia and how far along in pregnancy a woman is. [4] Blood pressure medication, such as labetalol and methyldopa, may be used to improve the mother's condition before delivery. [6] Magnesium sulfate may be used to prevent eclampsia in those with severe disease. [4]
A systolic blood pressure (the top number) of greater than 140 mmHg and/or a diastolic blood pressure (the bottom number) of greater than 90 mmHg is higher than the normal range. If the blood pressure is high on at least two separate occasions after the first 20 weeks of pregnancy and the woman has signs of organ dysfunction (e.g. proteinuria ...
During pregnancy, the challenge is to determine when to use antihypertensive medications and which level of blood pressure to target. [30] A balance has to be found between the potential risk to the health of the baby related to drug-exposure and the risk to the mother and baby due to an untreated medical condition (severe hypertension). [31]
Anti-hypertensives are blood pressure medications used to treat high blood pressure in pregnant women. [38] This class of medication is commonly used to treat problems such as heart failure, heart attack, and kidney failure. [38] Caution must be exercised with the use of various hypertensive agents for the treatment of blood pressure. [57]
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
Amlodipine, sold under the brand name Norvasc among others, is a calcium channel blocker medication used to treat high blood pressure, coronary artery disease (CAD) [10] and variant angina (also called Prinzmetal angina or coronary artery vasospasm, among other names). [11]